Hollywood star Jennifer Aniston has some real famous friends! Here's a look at 10 of Aniston's closest celebrity friends.

It became clear to the world that Jennifer Aniston is wildly popular after her 50th birthday guest list was released. Well-known celebrities like Reese Witherspoon, George Clooney, Robert Downey Jr., Katy Perry, Gwyneth Paltrow, Demi Moore, John Mayer, Orlando Bloom, Barbra Streisand, Kate Hudson, Keith Richards, Laura Dern, and Jennifer Meyer. Some of her costars from Friends were there too!

10.Courteney Cox & Jennifer Aniston Were BFFs On Friends & Are BFFs IRL

It is obvious to anyone who looks their way that Courteney Cox and Jennifer Aniston have a real and true friendship that goes far beyond their time filming Friends together in the 90s. They played the roles of Monica and Rachel! Sure, the set of that show is where they met and first connected with each other but they have chosen to remain friends in real life for years!

9.Jennifer Aniston & Adam Sandler Have A Great Rapport

Jennifer Aniston and Adam Sandler are great friends and the fact that they chose to film two movies together pretty much cements that fact in stone for us. In 2011, the pair starred in Just Go With It, a film about a man trying to deceive a lovely younger woman by pretending to be a successful divorcee. The comedy also starred Brooklyn Decker.

8.Brad Pitt & Jennifer Aniston Divorced But Are Now Friend

Brad Pitt and Jennifer Aniston used to be a couple but when a major scandal shook the world, they split ways. He entered into a relationship with Angelina Jolie, leaving a lot of people to speculate that some cheating might have occurred. He is now divorced from Jolie.

7.Jennifer Aniston & Ben Stiller Go Way Back

Jennifer Aniston and Ben Stiller go way back because he guest-starred on an episode of Friends in the 90s. He played the role of Tommy in the episode "The One With The Screamer" in the 22nd episode of the third season. Having someone as funny as him on Friends was a great bonus!

6.Jennifer Aniston & Alicia Keys Connect Over Women's Health Issues

When two people have matching views about what is important in the world, creating a friendship is very easy. For Jennifer Aniston and Alicia Keys, their joint views allow them to have an awesome friendship. These two, plus Demi Moore, worked together to release a Lifetime film series called Five. The film series is about women fighting back against breast cancer.

5.Jennifer Aniston & Chelsea Handler Share Laughs Often

Chelsea Handler is a hilarious comedian. She might occasionally be controversial but most of her fans really do not think twice about her sense of humor because of how funny and personable she is. Obviously, Jennifer Aniston feels the same way! These two hang out and share some great laughs.

4.Jennifer Aniston & David Schwimmer Played Lovers On Friends

Jennifer Aniston and David Schwimmer played lovers on Friends. The romance between the characters these two played on the show was a big deal for everyone watching. She played the role of Rachel Green and he played Ross Geller. Seeing the characters they played on the show end up together was pretty magical!

3..Selena Gomez & Jennifer Aniston Sparked Up A Friendship

According to The Blast, the friendship between Selena Gomez and Jennifer Aniston was created organically. Gomez told Vanity Fair that when she first ran into Aniston, "My heart stopped and I freaked out and I ran to my mom!" Gomez, much like plenty of other young adults, very likely grew up watching Aniston on Friends.

2.Jennifer Aniston & Ellen Degeneres Are Pretty Tight

Jennifer Aniston and Ellen Degeneres are pretty tight in real life even though a lot of the times we have seen these two together have been on Ellen's talk show for interviews. The interview banter these two have is witty and hilarious. Watching Aniston get asked questions by Degeneres is super comical!

1.Jay Leno & Jennifer Aniston Have Had Some Hilarious Interview Moments

Jay Leno and Jennifer Aniston have had some great interview moments, similar to the funny moments Aniston has had on The Ellen DeGeneres Show over the years. Leno has been the host of NBC's The Tonight Show with Jay Leno from 1992 to 2009. He had a great run during that era of time.